Final answer:
The American city with the suffix '-polis' in its name is Indianapolis, reflecting the influence of Greek language and political concepts on American toponyms.
Step-by-step explanation:
An American city with the suffix "-polis" in its name is Indianapolis. This suffix comes from the Ancient Greek word "polis", which refers to a city or city-state and is related to political and urban concepts.
While cities like Atlanta, Mobile, and Richmond have historical significance due to events like the Bread Riots, and Philadelphia for its importance during the Revolutionary War, Indianapolis is the example from the given options that actually contains the '-polis' suffix.