Final answer:
Jewish people and Italians had the hardest time becoming acculturated to the US due to discrimination and anti-Semitism, as well as differences in appearance, language, religion, and food.
Step-by-step explanation:
The immigrant group that had the hardest time becoming acculturated to the US were Jewish people and Italians. These more recent immigrants often faced discrimination and anti-Semitism. They were seen as different due to their appearance, language, religion, and even the food they ate. This made them easy targets for hatred and discrimination, especially when jobs and housing were scarce.