Final answer:
The liver and kidney are the two main organs where hormones are broken down in the body.
Step-by-step explanation:
The two main organs where hormones are broken down in the body are the liver and the kidney. The liver is responsible for the degradation of peptide hormones, while the kidney plays a role in breaking down peptide hormones as well as other hormones like catecholamines, steroids, and thyroid hormones. Hormones are broken down through enzymatic modification in the blood and/or in these organs.