Final answer:
The recombination of V, D, and J Ig gene segments is effected by an enzyme called DNA recombinase. This enzyme randomly excises most of the V and J segments from the gene and splices one V segment to one J segment. Recombination and splicing can result in millions of possible VJ combinations.
Step-by-step explanation:
The recombination of V, D, and J Ig gene segments is effected by an enzyme called DNA recombinase.
This enzyme randomly excises most of the V and J segments from the gene and splices one V segment to one J segment. During RNA processing, all but one V and J segment are spliced out.
Recombination and splicing can result in over 106 possible VJ combinations, leading to the production of unique antibody molecules in each differentiated B cell.