Question

selection needed so thymocytes will produce T cell repertoire capable of interacting with self-MHC molecules

Answer 1

Thymocytes produce a T cell repertoire capable of interacting with self-MHC molecules through positive selection during thymic selection.

Step-by-step explanation:

During thymic selection, thymocytes are exposed to MHC (major histocompatibility complex) proteins presented by thymic epithelial cells. Thymocytes that can successfully bind to these MHC proteins continue to mature, while those that cannot undergo apoptosis. This process is known as positive selection, as it selects thymocytes that can interact with self-MHC molecules.