Question

Describe a recessive (tumor suppressor) loss-of-function mutations. Provide an example

Answer 1

Tumor suppressor genes are genes that normally slow down or stop cell division. When a mutation occurs in a tumor suppressor gene, it can lead to uncontrolled cell growth and cancer. An example of a recessive (tumor suppressor) loss-of-function mutation is the BRCA1 gene mutation.

Step-by-step explanation:

Tumor suppressor genes are genes that normally slow down or stop cell division. When a mutation occurs in a tumor suppressor gene, it can no longer control cell division.

This can lead to uncontrolled cell growth and the development of cancer.

An example of a recessive (tumor suppressor) loss-of-function mutation is the BRCA1 gene mutation, which is associated with an increased risk of breast and ovarian cancers.