Final answer:
If cell division fails to occur following DNA replication in a germ line cell, it can result in an abnormal number of chromosomes in gametes, leading to chromosomal disorders.
Step-by-step explanation:
If cell division fails to occur following DNA replication in a germ line cell, the entire diploid set could be affected. The failure of cell division can lead to the abnormal number of chromosomes in gametes, which can result in chromosomal disorders. For example, if sister chromatids fail to separate during meiosis II, the result is one gamete with an extra chromosome, two normal gametes, and one gamete missing a chromosome.