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Class of MHC molecules will be utilized for intracellular vs. extracellular pathogens

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User Desoga
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1 Answer

4 votes

Final answer:

Intracellular pathogens are presented by class I MHC molecules, while extracellular pathogens are presented by class II MHC molecules.

Step-by-step explanation:

Antigens from extracellular pathogens are processed and presented in the binding cleft of class II MHC molecules. This interaction is strengthened by the protein CD4, which is associated with helper and regulatory T cells. On the other hand, antigens from intracellular pathogens are presented by class I MHC molecules, and this interaction is strengthened by the protein CD8, which is associated with cytotoxic T cells.

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User Duoc Tran
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