During a B cell's lifespan, changes occur in the Ig genes. Transcription is activated when the B cell coexpresses surface IgM and IgD. This recombination process creates diverse immunoglobulin antibody molecules.
During the lifespan of a B cell, changes occur in the Ig genes. Transcription is activated when the B cell coexpresses surface IgM and IgD. These genes, known as immunoglobulin genes, recombine to create diverse V-D-J-C immunoglobulin antibody molecules. This recombination process occurs during the maturation of stem cells in the bone marrow.
Learn more about Ig genes during B cell's lifespan