asked 92.2k views
4 votes
Which complex is comprised of Brf, B" and TBP?

-TFIIIB
- TFIIIC
- TFIIB
- SL1

1 Answer

4 votes

Final answer:

TFIIIB is the complex made up of Brf, B" and TBP, and it plays a critical role in forming the transcription initiation complex necessary for the synthesis of mRNA in eukaryotic cells.

Step-by-step explanation:

The complex in question, comprised of Brf, B" and TATA-binding protein (TBP), is TFIIIB. During the initiation phase of transcription in eukaryotes, multiple transcription factors are required to recruit RNA polymerase II to the promoter of a protein-coding gene. Among these, TFIIIB is part of a larger group of basal transcription factors, each denoted by 'TFII' followed by a specific letter. TFIIIB is essential in the recruitment and assembling of transcription factors and polymerase to form the transcription initiation complex, allowing it to start synthesizing mRNA.

answered
User Asyranok
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