Question

Which of the following is most likely attributable to base substitution at a 5' splice junction

a. a longer than usual final transcript
b. an amino acid substitution in the final protein product
c. a shorter than usual final transcript
d. failure of the U2 snRNP to bind the transcript

Answer 1

A base substitution at a 5' splice junction is most likely attributable to a shorter than usual final transcript.

Step-by-step explanation:

A base substitution at a 5' splice junction is most likely attributable to a shorter than usual final transcript. When there is a base substitution at the 5' splice junction, it can disrupt the normal splicing process, leading to the exclusion of an exon and resulting in a shorter mRNA transcript.