Question

Which of the following is considered to be the "master regulator" of terminal plasma cell differentiation?

A. Blimp-1
B. IRF-4
C. Pax-5
D. Bcl-6
E. NF-κB

Answer 1

The "master regulator" of terminal plasma cell differentiation is Blimp-1. Blimp-1 is a transcription factor that plays a critical role in the differentiation of B cells into plasma cells.

Step-by-step explanation:

The "master regulator" of terminal plasma cell differentiation is Blimp-1. Blimp-1 is a transcription factor that plays a critical role in the differentiation of B cells into plasma cells. It suppresses the expression of genes that promote B cell identity and activates genes involved in plasma cell function, such as antibody production.