Question

Attachment of an integrin to its ligand can induce which of the following responses within a cell?

a-changes in cytoplasmic pH
b-changes in cytoplasmic C2+ ion concentration
c-protein phosphorylation
d-gene expression

Answer 1

When an integrin binds to its ligand, it can induce b) changes in cytoplasmic pH, b) cytoplasmic Ca2+ ion concentration, c) protein phosphorylation, and d) gene expression. Hence, all the options are correct.

Step-by-step explanation:

When an integrin binds to its ligand, it can induce changes in cytoplasmic pH, cytoplasmic Ca2+ ion concentration, protein phosphorylation, and gene expression.

For example, binding of epidermal growth factor (EGF) to its receptor tyrosine kinase can lead to changes in gene expression. Similarly, the binding of adrenaline to a G-protein-linked receptor can promote cellular metabolism, and the binding of EGF to its receptor tyrosine kinase can promote cell division.

Overall, the attachment of an integrin to its ligand can trigger a variety of responses within a cell, including changes in pH, ion concentration, protein phosphorylation, and gene expression.