Final answer:
The Hardy-Weinberg equilibrium principle in biology describes a situation in which allele frequencies at a locus remain constant generation after generation, disallowing the effects of natural selection, mutation, genetic drift, and migration (gene flow).
Step-by-step explanation:
The situation described, in which the allele frequencies at a locus tend to remain the same generation after generation, is known as the Hardy-Weinberg equilibrium in biology. According to the Hardy-Weinberg equilibrium principle, allele frequencies in a population will remain constant in the absence of natural selection, mutation, genetic drift, and migration (gene flow). This principle allows scientists to predict allele frequencies and make inferences about evolutionary forces at play.