Question

Which lysosomal storage disorder is an inherited disorder that causes large, fused lysosomes within the cytoplasm and may have a slight effect of bleeding due to platelet function being abnormal?

1) Smudge cells
2) Chédiak-Higashi syndrome
3) Siderotic granules
4) Briman cat neutrophil granulation

Answer 1

Chédiak-Higashi syndrome is an inherited lysosomal storage disorder that causes large, fused lysosomes and can affect platelet function, potentially leading to abnormal bleeding.

Step-by-step explanation:

The lysosomal storage disorder that causes large, fused lysosomes within the cytoplasm and may have a slight effect on bleeding due to abnormal platelet function is Chédiak-Higashi syndrome. This inherited disorder is characterized by the dysfunction of lysosomes, resulting in the formation of giant lysosomes. These enlarged lysosomes impair normal cellular functions, including platelet function, leading to the potential for abnormal bleeding.