Question

Lysosomal enzymes are transported from the TGN in vesicles coated with what protein?

1) clathrin
2) lysozyme
3) dynamin
4) COPI
5) COPII

Answer 1

Lysosomal enzymes are transported from the TGN in vesicles coated with the clathrin protein. Once internalized, the coated vesicles fuse with an early endosome to form a sorting vesicle, which eventually becomes a lysosome. Digestive enzymes in the lysosome catalyze hydrolysis of the vesicle contents.

Step-by-step explanation:

Lysosomal enzymes are transported from the TGN in vesicles coated with the clathrin protein. Once internalized, the coated vesicles lose their clathrin coat and fuse with an early endosome to form a sorting vesicle. In the vesicle that remains, now a lysosome, digestive enzymes catalyze hydrolysis of the vesicle contents.