Question

Which one of the following pathogens expresses a bacterial surface protein that indirectly recruits the Arp2/3 complex to nucleate actin polymerization?

1) Salmonella enterica
2) Escherichia coli
3) Staphylococcus aureus
4) Listeria monocytogenes

Answer 1

Listeria monocytogenes expresses a bacterial surface protein called ActA that indirectly recruits the Arp2/3 complex to nucleate actin polymerization.

Step-by-step explanation:

Listeria monocytogenes, a facultative intracellular pathogen, is the pathogen that expresses a bacterial surface protein that indirectly recruits the Arp2/3 complex to nucleate actin polymerization. This surface protein is known as actin assembly-inducing protein (ActA) and it is expressed on the surface of Listeria. ActA binds to the Arp2/3 complex, which then nucleates actin polymerization, enabling the bacterium to produce actin tails and move within the host cell.