Final answer:
The one gene-one enzyme hypothesis was modified to the "one gene-one polypeptide" hypothesis.
Step-by-step explanation:
The one gene-one enzyme hypothesis was modified to the "one gene-one polypeptide" hypothesis. This revision was made after subsequent knowledge about the processes of transcription and translation in cells.
The one gene-one polypeptide hypothesis reflects the understanding that each gene codes for a single polypeptide chain, which may be a component of a larger protein molecule.