Question

Knockout mice can be obtained after homologous recombination of a cloned mutant allele with the cellular gene in embryonic stem (ES) cells.

a. True
b. False

Answer 1

False. Knockout mice can be obtained after homologous recombination of a cloned mutant allele with the cellular gene in embryonic stem (ES) cells.

Step-by-step explanation:

False. Knockout mice can be obtained after homologous recombination of a cloned mutant allele with the cellular gene in embryonic stem (ES) cells. This process involves introducing a mutant allele into the ES cells, which results in the disruption of the targeted gene in the mouse. The disrupted gene can then be passed on to offspring, creating knockout mice that lack a specific gene or have it modified.