Question

What FISH technique is most useful for detection of multiple complex genomic mutations?

1) Fluorescence in situ hybridization (FISH)
2) Polymerase chain reaction (PCR)
3) Next-generation sequencing (NGS)
4) Western blotting

Answer 1

Next-generation sequencing (NGS) is the most useful FISH technique for detection of multiple complex genomic mutations.

Step-by-step explanation:

The most useful FISH technique for detection of multiple complex genomic mutations is Next-generation sequencing (NGS). NGS is a high-throughput sequencing technology that enables the simultaneous sequencing of millions of DNA fragments.

It can detect a wide range of mutations, including single nucleotide variants, insertions, deletions, and structural variations. NGS is particularly useful for studying complex genomic disorders where multiple mutations are involved.