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In the first step of glycolysis, glucose becomes glucose 6-phosphate. Where does the phosphate on the sixth carbon of glucose come from?

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Final answer:

During glycolysis, the sixth carbon of glucose is phosphorylated using ATP, resulting in glucose-6-phosphate. The phosphate group comes from ATP, which is the donor of the phosphate group.

Step-by-step explanation:

In glycolysis, the phosphate on the sixth carbon of glucose comes from ATP, which is the donor of the phosphate group. In the first step, hexokinase phosphorylates glucose using ATP to form glucose-6-phosphate. This phosphorylation makes glucose more reactive and keeps it inside the cell.

Then, phosphofructokinase adds another phosphate group from ATP, converting glucose-6-phosphate into fructose-1,6-bisphosphate.

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