Final answer:
The Al-Aqsa Mosque and Dome of the Rock are located in Jerusalem on the Temple Mount in the Old City. The Dome of the Rock is one of the oldest works of Islamic art and holds religious significance for multiple faiths.
Step-by-step explanation:
The Al-Aqsa Mosque and Dome of the Rock are located in Jerusalem, specifically on the Temple Mount in the Old City. The Al-Aqsa Mosque is considered the third holiest site in Islam and is associated with the Prophet Muhammad. The Dome of the Rock, built adjacent to the mosque, holds religious significance for multiple faiths and is one of the oldest works of Islamic art.