Final answer:
The compound-solvent combination with the highest expected antioxidant activity is likely Compound 2 in water because antioxidants are generally polar and dissolve better in polar solvents like water.
Step-by-step explanation:
To determine which compound-solvent combination would show the highest antioxidant activity, we need to consider the solubility principles of 'like dissolves like,' meaning that polar solutes are more likely to dissolve in polar solvents, and nonpolar solutes in nonpolar solvents. Without specific details about Compound 1 and Compound 2, we must assume general cases. Typically, antioxidants are polar because they need to be soluble in water-based cellular environments to be effective. Therefore, it is likely that Compound 2 in water would show the highest antioxidant activity because water is a polar solvent and would better support the dissolution of a polar antioxidant compound, thereby increasing its bioavailability and efficacy.