Question

"Lysosomes digest food particles brought into a cell by endocytosis. After a vesicle containing food particles fuses with a lysosome, H' ions are transported into the lysosome from the cytosol.

This significantly lowers the pH of the lysosome relative to the cytosol and activates the enzymes that digest the particles
Which of the following best predicts what will happen to the lysosomal enzymes if the proteins that transport Hions fromne cytosol into the lysosome are damaged?

A The lysosomal enzymes will not become active, since there will be no active transport of H' ions.
B The lysosomal enzymes will not become active, since Hions will diffuse out of the lysosome.
C The lysosomal enzymes will become active, since facilitated diffusion will move Hions into the lysosome.
D The lysosomal enzymes will become active, since passive diffusion will move H ions into the lysosome."

Answer 1

The lysosomal enzymes will not become active, since there will be no active transport of H+ ions.

Step-by-step explanation:

The best prediction for what will happen to the lysosomal enzymes if the proteins that transport H+ ions from the cytosol into the lysosome are damaged is option A: The lysosomal enzymes will not become active, since there will be no active transport of H+ ions.

The enzymes inside lysosomes, called acid hydrolases, are activated by the low pH inside the lysosome, which is maintained by proton pumps that transport H+ ions into the lysosome. If the proteins that transport H+ ions are damaged, there will be no active transport of H+ ions into the lysosome, resulting in a higher pH and a failure to activate the enzymes. The enzymes will remain inactive, and digestion of the food particles will not occur.

It is important to note that options B, C, and D are incorrect because they suggest that H+ ions will enter the lysosome through diffusion, facilitated diffusion, or passive diffusion, respectively. However, active transport by proton pumps is necessary to maintain the lower pH inside the lysosome.