Final answer:
Non-depolarizing NMBs competitively block the action of acetylcholine at the neuromuscular junction without causing initial depolarization. Examples of non-depolarizing NMBs include rocuronium, vecuronium, and pancuronium.
Step-by-step explanation:
Non-depolarizing neuromuscular blockers (NMBs) work by competitively blocking the action of acetylcholine at the neuromuscular junction. These drugs bind to the nicotinic acetylcholine receptors on the motor end plate, preventing the transmission of nerve impulses to the muscle fibers.
Unlike depolarizing NMBs, which cause a depolarization and fasciculation before blocking the neuromuscular junction, non-depolarizing NMBs directly inhibit the neuromuscular junction without causing any initial depolarization.
Examples of non-depolarizing NMBs include rocuronium, vecuronium, and pancuronium.