Final answer:
The molecular signaler that increases fibrosis in muscle is TGF-β (Transforming Growth Factor Beta). TGF-β stimulates the proliferation of fibroblasts, leading to the production of collagen and the development of fibrosis in muscle.
Step-by-step explanation:
The molecular signaler that increases fibrosis in muscle is TGF-β (Transforming Growth Factor Beta).
TGF-β is a cytokine that plays a crucial role in promoting the formation of scar tissue or fibrosis. In the context of muscle, TGF-β stimulates the proliferation of fibroblasts, leading to the production of collagen and the development of fibrosis.
For example, in conditions such as muscular dystrophy or chronic muscle injury, the ongoing inflammation and tissue damage can trigger the release of TGF-β, which initiates fibrotic processes.