Question

Regions of TCRs and BCRs that are particularly variable in their amino acid sequences are known for _____

A. binding to antigen.
B. sticking to denatured proteins.
C. spanning the plasma membrane.
D. binding to adaptor proteins.
E. becoming phosphorylated.

Answer 1

Regions of TCRs and BCRs with variable amino acid sequences are known for binding to antigens, providing the molecular basis for the recognition of diverse antigens.

Step-by-step explanation:

Regions of T cell receptors (TCRs) and B cell receptors (BCRs) that are particularly variable in their amino acid sequences are known for binding to antigens. These variable regions are responsible for determining the antigenic specificity of the receptors. TCRs consist of two chains, each with two domains. The variable region domain is what allows TCRs to recognize a vast diversity of antigens, as it combines the amino acid sequences of both chains. Similarly, BCRs bind specific antigen epitopes with their variable Fab antigen-binding regions, providing a similarly vast array of antigen recognition capabilities.