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If both D-J rearrangements are nonproductive, the early pro-B cell dies by apoptosis before V-DJ rearrangement occurs.

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User Omoman
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1 Answer

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Final answer:

If both D-J rearrangements are nonproductive, the early pro-B cell dies by apoptosis before V-DJ rearrangement occurs.

Step-by-step explanation:

Apoptosis is a programmed cell death process that is initiated when cells are no longer necessary or when they are genetically or otherwise damaged.

In the case of nonproductive D-J rearrangements, it means that the rearrangement of DNA segments in the light chain gene does not result in the formation of a functional B cell receptor. As a result, the cell undergoes apoptosis as part of the normal immune system development process.

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User Tigerrrrr
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