Final answer:
The kidneys primarily control the ions Sodium (Na+), Potassium (K+), Calcium (Ca2+), and Chloride (Cl-).
Step-by-step explanation:
The primary ions controlled by the kidneys are Sodium (Na+), Potassium (K+), Calcium (Ca2+), and Chloride (Cl-).
The kidneys play a crucial role in maintaining the balance of these ions in the blood. For example, they regulate the reabsorption of sodium and excretion of potassium in the renal collecting tubule. They also help maintain calcium concentrations through the action of hormones such as PTH, calcitriol, and calcitonin. Additionally, the kidneys regulate chloride levels by excreting more or less chloride in the urine as needed.