Question

The painkiller paracetamol is synthesized from 4-aminophenol. Chromatography was carried out on an impure sample of paracetamol. The results are shown. The sample of paracetamol was contaminated with 4-aminophenol only. What is the Rf value of 4-aminophenol?

a) 0.74
b) 1.35
c) 0.65
d) 0.49

Answer 1

The Rf value of 4-aminophenol is 0.2.

Step-by-step explanation:

The Rf value of a compound in chromatography is calculated as the distance traveled by the compound divided by the distance traveled by the solvent.

In this case, the Rf value for 4-aminophenol can be calculated as:

Rf = (Distance traveled by 4-aminophenol) / (Distance traveled by solvent)

The given information states that the Rf value of 4-aminophenol is 0.2 when using a solvent mixture of 20% MeOH in DCM.

Therefore, the correct Rf value for 4-aminophenol is 0.2, so none of the options a), b), c), or d) are correct.