Which statement about cell cycle checkpoints are true for mammalian cells?
a.DNA damage detection system play the pivotal role in activation of check in cell cycle.
b.Damage to membrane proteins activate cell cycle checkpoints.
c.Dysfunstional mRNA formation by splicing activate cell cycle checkpoints.
d. Failure of spindle fibre binding to kinetochore lead to activation of cell cycle checkpoints.
e. Activation of cell cycle checkpoints provide time for the dividing cells to overcome my molecular problems