Question

4. Activation of mu-opioid receptors by fentanyl inhibits the release of which of the

following
neurotransmitters?
a. Gamma-aminobutyric acid (GABA), which reduces neuronal activity
b. Substance P, which is involved in pain transmission
c. Glutamate, which is involved in pain transmission
d. All of the above

Answer 1

The activation of mu-opioid receptors by fentanyl inhibits the release of substance P which is involved in pain transmission.

Step-by-step explanation:

The activation of mu-opioid receptors by fentanyl inhibits the release of substance P which is involved in pain transmission. Fentanyl does not directly inhibit the release of gamma-aminobutyric acid (GABA), which reduces neuronal activity, or glutamate, which is also involved in pain transmission. Therefore, the correct answer is b. Substance P.

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