Final answer:
A region is an area with specific characteristics that differentiate it from other areas, which can be based on geography, politics, or culture.
Step-by-step explanation:
The term that means an area with particular geographic, political, or cultural characteristics that set it apart from other areas is region. A region can be defined by physical features such as landforms, climate, and vegetation, as well as by political boundaries and cultural practices. For example, the Amazon rainforest region in South America is distinct because of its unique biodiversity, while the European Union is a region defined by a common political and economic integration.
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