Question

MicroRNA (miRNA) production occurs in several steps. Arrange the following statements describing the production and function of miRNAs in the order in which they occur A. The RNA binds to proteins to form the RNA-induced silencing complex B. The miRNA gene is transcribed to produce a primary transcript. C. The RNA strand that is complementary to the iRNA is degraded. D. A short RNA molecule with a hairpin loop structure is produced

E. Dicer protein produces a double-stranded RNA molecule

Answer 1

B. The miRNA gene is transcribed to produce a primary transcript.

E. Dicer protein produces a double-stranded RNA molecule

A. The RNA binds to proteins to form the RNA-induced silencing complex

D. A short RNA molecule with a hairpin loop structure is produced

C. The RNA strand that is complementary to the iRNA is degraded.

The production and function of miRNAs occur in several steps:

The miRNA gene is transcribed to produce a primary transcript.

Dicer protein produces a double-stranded RNA molecule.

One strand of the double-stranded RNA molecule, the miRNA, is selected for further processing.

The miRNA forms a hairpin loop structure.

The miRNA binds to proteins to form the RNA-induced silencing complex (RISC).

The RNA strand that is complementary to the miRNA is degraded.

The miRNA regulates gene expression by binding to the mRNA and inhibiting its translation or promoting its degradation.