Question

What is the complimentary DNA sequence

for each of the following:
a) 5' TCGTAGGCT 3'
b) 3' CCGAATGCAT 5'

Answer 1

a) 3' AGCATCCGA 5'

b) 5' GGCTTACGTA 3'

Step-by-step explanation:

Based on complementary base pairing rules, T pairs with A, whereas C pairs with G.

In addition, because complementary strands run in complementary opposing directions, if the original sequence is in the 3' → 5' direction, our new strand is in the 5' → 3' direction, and the opposite for the original sequence that starts in the 5' → 3' direction.