The Klinefelter syndrome is a consequence of non-disjunction mutation. It is simply understood as having an extra X chromosome for males. The Klinefelter syndrome can be a result during cell divisions either of meiotic or mitotic cell divisions. There is an imbalance of the division of cell and this resulting to Klinefelter syndrome. When a male was born, it usually has one X and one Y chromosome but in this case, a male can have one or more X chromosome. This syndrome common leads for the males having unusual physical attributes.