Ryan's marbles = x
Marie has 4 times less marbles then Ryan would have if he lost 15 marbles (it means he would have x-15) 
So, Marie marbles = (x-15):4
If Ryan lost 75 marbles (it means he would have x-75), he would have 1 1/2 times as many marbles as Marie.
We got an equation: 
 
   
 Multiply both sides by 8: 
 
 
Add 600 and subtract 3x on both sides: 

Divide both sides by 5: 

Answer: Ryan have 111 marbles.