Both aerobic and anaerobic respirations are types of cellular respiration. Both use glycolysis to produce ATP. Both generate energy by breaking down glucose. Both produce byproducts and depend on chemical reactions that are localized in the cytosol. Both use pyruvate as a substrate and both processes depend on enzymes to catalyze their respective chemical reactions. A fact about these two types of respiration is that aerobic respiration produces or release 19 times more energy than anaerobic respiration from the same amount of glucose