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How did the use of Spanish missions affect the spread of disease in the Americas

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Answer:The answer is C they were exposed to disease

Step-by-step explanation:

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User Gil Stal
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The native Americans had no immunity for European disease and the missionaries, although in their opinion with good intentions, brought with them the disease to the indigenous population. The effect was a mass-scale death, up to 30 % in some areas.
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User Nick Price
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