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Centromeres split apart during

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User Zdenekca
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The centromeres do not separate during anaphase I, but during anaphase II in meiosis. In mitosis the centromeres split during anaphase.

Explanation:

Anaphase I begins when the two chromosomes of each bivalent (tetrad) depart and start driving toward opposite posts of the cell as a consequence of the action of the spindle. Mark that in anaphase I the sister chromatids remain connected at their centromeres and move collectively toward the poles.

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User Waweru
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Anaphase is the shortest phase of mitosis. In this stage, the centromeres split apart. Spindle fibers pull the two sister chromatids apart and direct them to opposite ends of the cell. Once these chromatids are separated, they are referred to as daughter chromosomes.
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User Prince Owen
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