Question

In South America, the dominant culture in the region is seen as a hazard to the way of life of the Native Americans, weakening their _____.

Answer 1

I think that the "dominant" culture here is the Spanish-language, Latino culture, which is slowly taking over the indigenous cultures, for example by replacing their languages and religion (Christianity instead of the indigenous religions).

I would finish the sentence with "culture" or "religion" or "self-esteem".