Okay we'll start easy
46*93
We will take 6*3 which is 18.
40*3 which is 120
6*90 which is 540
40*90 which is 3600
Now add up those
18+120+540+3600 which is 4278
So the missing numbers.
3._00 is going to be 3600
5_0 is going to be 540
_20 is going to be 120
1_ is going to be 18
4._78 is going to be 4.278
Hope this helped. ^~^