Hello! For this you are just going to do this step by step, and remember to use PEMDAS. That is the order in which you should do the math. The abbreviation stands for Parenthesis, exponents, multiplication, division, addition and subtraction. So lets get started!
((15y0x−3z23x3)(y7)z12)2=254x6y14z6x6=254y14z6
Hope this helps!! If you need any more help or further explanation just let me know!! :)