For me, one is getting use to new surroundings. We can get so used to the way we do things that we fall into a routine. Another is missing your loved ones because it gets lonely when people you love aren’t there. Then there is adjusting to the way things work. New place means new set of rules that you have to adapt to. Finally there is letting go of the things you hold dear. It’s hard to let go but you have to open yourself to new possibilities.