The most inappropriate biochemical response to low blood sugar would by Inhibit glycolysis. When Inhibited glycolysis occurs, Hexokinase, the enzyme that is responsible of the catalyzing the first step in the glycolys process, is inhibited by the product it creates, glucose 6-phosphate. This causes the glucose 6-phosphate to rise more than it should due to the equilibrium with fructose 6-phosphate,