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Both the ___ and the ___ must be functioning correctly to come out of a comatose state.

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User Sayhaha
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The answers are the cerebral cortex and the reticular activating system (RAS). When someone is in a comatose state, they exhibit a complete absence of consciousness. These two important neurological components must be functioning correctly so an individual can come out of a coma.
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User Telaclavo
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