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One of the most significant political consequences that resulted from the spread of cotton agriculture across the south into the southwest of the nation was that

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User Snor
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The most significant political consequence was creating an economy of slavery. This caused a massive devide in the United States which in turn caused a massive civil war in which millions died. It caused the south to rely on slave labor and unable to provide any sort of ethical and moral economy.
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User Asiyah
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