Question

The tnf signaling pathway stimulates both an apoptosis and a cell survival pathway in the same cell. what molecular mechanism determines whether the cell survives or dies? choose one correct answer.

Answer 1

Cell death or survival in a TNF receptor stimulated cell is determined by the relative expression level of downstream signaling proteins in the proapoptotic and anti-apoptotic pathways Cell death or survival in a TNF receptor stimulated cell is determined by the signals received from neighboring cells. If the neighboring cell is secreting "survival" stimulants, then the TNF receptor stimulated cell will also survive