Question

How did Mesopotamia change the nomadic way of life

Answer 1

Mesopotamia was the first civilization.  They focused on agriculture and livestock.  This changed from the hunting and gathering lifestyle from before.  However, now that they became sedentary, diseases from animals began to appear.

Answer 2

Mesopotamia introduced a more sedentary way of life by means of agriculture and animal husbandry. So for example, instead of the nomadic way of life, which is/was going hunting, foraging, and/or fishing.
Hopefully this is right and helpful. Good luck!