Question

IL-1B is a protein released by cells under conditions of infection. Excessive release of IL-1B can be very damaging and can lead to severe disease. In a typical experiment, the typical concentration of IL-1B around stressed cells is 800 t 113 pg/ml. A researcher is testing drugs that can inhibit IL-1B release. She tests two drugs, drug-1 and drug-2, for their effects on IL-1B release. If the drugs have a z-score of -2.5, she will consider them promising for future study. In her experiment, stressed cells treated with drug-1 yielded 1104 pg/ml of IL-1B, while yielded 540 pg/ml of IL-18. Is she going to continue studying either drug, and if so, which one?

Answer 1

She will not study drug-2 or drug-1.

Answer 2

The researcher will not continue with the study.

Explanation:

In the cases, the results have more negative values.

A lower z-score means less confidence in the results.

Therefore, the researcher will cease all the studies and further research work.